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1

Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain

Gadkar, Kapil, Yadav, Daniela Bumbaca, Zuchero, Joy Yu, Couch, Jessica A., Kanodia, Jitendra, Kenrick, Margaret K., Atwal, Jasvinder K., Dennis, Mark S., Prabhu, Saileta, Watts, Ryan J., Joseph, Sean

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

2

BRCA2 germline mutations in male breast cancer cases and breast cancer families

Couch, Fergus J., Farid, Linda M., DeShano, Michelle L., Tavtigian, Sean V., Calzone, Kathleen, Campeau, Lisa, Peng, Yi, Bogden, Bert, Chen, Qian, Neuhausen, Susan

Journal:

Nature Genetics

Year:

1996

File:

PDF, 306 KB

1996

3

A review of a multifactorial probability based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS)

Noralane M. Lindor, Lucia Guidugli, Xianshu Wang, Maxime P. Vallée, Alvaro N. A. Monteiro, Sean Tavtigian, David E. Goldgar, Fergus J. Couch

Journal:

Year:

2012

Language:

english

File:

PDF, 107 KB

english, 2012

4

Why linked data is not enough for scientists

Sean Bechhofer, Iain Buchan, David De Roure, Paolo Missier, John Ainsworth, Jiten Bhagat, Philip Couch, Don Cruickshank, Mark Delderfield, Ian Dunlop, Matthew Gamble, Danius Michaelides, Stuart Owen,

Journal:

Future Generation Computer Systems

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

5

Lateral accretion in a straight slope channel system: an example from the Forties Sandstone of the Huntington Field, UK Central North Sea

Edwards, Chris, McQuaid, Sean, Easton, Stewart, Scott, Don, Couch, Andrew, Evans, Ron, Hart, Stephen

Journal:

Geological Society, London, Petroleum Geology Conference series

Year:

2017

Language:

english

File:

PDF, 15.49 MB

english, 2017

6

Classification of missense substitutions in the BRCA genes: A database dedicated to Ex-UVs

Maxime P. Vallée, Tiana C. Francy, Megan K. Judkins, Davit Babikyan, Fabienne Lesueur, Amanda Gammon, David E. Goldgar, Fergus J. Couch, Sean V. Tavtigian

Journal:

Year:

2012

Language:

english

File:

PDF, 200 KB

english, 2012

7

A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS)

Noralane M. Lindor, Lucia Guidugli, Xianshu Wang, Maxime P. Vallée, Alvaro N. A. Monteiro, Sean Tavtigian, David E. Goldgar, Fergus J. Couch

Journal:

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

8

Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer

Martin, Sean T, Matsubayashi, Hiroyuki, Rogers, Carmelle D, Philips, Juliet, Couch, Fergus J, Brune, Kieran, Yeo, Charles J, Kern, Scott E, Hruban, Ralph H, Goggins, Michael

Journal:

Year:

2005

Language:

english

File:

PDF, 156 KB

english, 2005

9

Integrated Evaluation of DNA Sequence Variants of Unknown Clinical Significance: Application to BRCA1 and BRCA2

David E. Goldgar, Douglas F. Easton, Amie M. Deffenbaugh, Alvaro N.A. Monteiro, Sean V. Tavtigian, Fergus J. Couch

Journal:

The American Journal of Human Genetics

Year:

2004

Language:

english

File:

PDF, 377 KB

english, 2004

10

A Systematic Genetic Assessment of 1,433 Sequence Variants of Unknown Clinical Significance in the BRCA1 and BRCA2 Breast Cancer–Predisposition Genes

Douglas F. Easton, Amie M. Deffenbaugh, Dmitry Pruss, Cynthia Frye, Richard J. Wenstrup, Kristina Allen-Brady, Sean V. Tavtigian, Alvaro N.A. Monteiro, Edwin S. Iversen, Fergus J. Couch, David E. Gold

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 729 KB

english, 2007

11

Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation

Chapman, Kathryn L., Holzgrefe, Henry, Black, Lauren E., Brown, Marilyn, Chellman, Gary, Copeman, Christine, Couch, Jessica, Creton, Stuart, Gehen, Sean, Hoberman, Alan, Kinter, Lewis B., Madden, Step

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

12

[IEEE 2010 IEEE 6th International Conference on E Science (e-Science) - Brisbane, Australia (2010.12.7-2010.12.10)] 2010 IEEE Sixth International Conference on e-Science - Why Linked Data is Not Enough for Scientists

Bechhofer, Sean, Ainsworth, John, Bhagat, Jiten, Buchan, Iain, Couch, Philip, Cruickshank, Don, Roure, David De, Delderfield, Mark, Dunlop, Ian, Gamble, Matthew, Goble, Carole, Michaelides, Danius, Mi

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

13

THE ROLE OF TURBULENCE IN NEUTRINO-DRIVEN CORE-COLLAPSE SUPERNOVA EXPLOSIONS

Couch, Sean M., Ott, Christian D.

Journal:

The Astrophysical Journal

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

14

REVIVAL OF THE STALLED CORE-COLLAPSE SUPERNOVA SHOCK TRIGGERED BY PRECOLLAPSE ASPHERICITY IN THE PROGENITOR STAR

Couch, Sean M., Ott, Christian D.

Journal:

The Astrophysical Journal

Year:

2013

Language:

english

File:

PDF, 921 KB

english, 2013

15

RADIATION TRANSPORT FOR EXPLOSIVE OUTFLOWS: A MULTIGROUP HYBRID MONTE CARLO METHOD

Wollaeger, Ryan T., van Rossum, Daniel R., Graziani, Carlo, Couch, Sean M., Jordan IV, George C., Lamb, Donald Q., Moses, Gregory A.

Journal:

The Astrophysical Journal Supplement Series

Year:

2013

Language:

english

File:

PDF, 673 KB

english, 2013

16

MULTI-DIMENSIONAL SIMULATIONS OF ROTATING PAIR-INSTABILITY SUPERNOVAE

Chatzopoulos, E., Wheeler, J. Craig, Couch, Sean M.

Journal:

The Astrophysical Journal

Year:

2013

Language:

english

File:

PDF, 571 KB

english, 2013

17

HIGH-RESOLUTION THREE-DIMENSIONAL SIMULATIONS OF CORE-COLLAPSE SUPERNOVAE IN MULTIPLE PROGENITORS

Couch, Sean M., O'Connor, Evan P.

Journal:

The Astrophysical Journal

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

18

AN IMPROVED MULTIPOLE APPROXIMATION FOR SELF-GRAVITY AND ITS IMPORTANCE FOR CORE-COLLAPSE SUPERNOVA SIMULATIONS

Couch, Sean M., Graziani, Carlo, Flocke, Norbert

Journal:

The Astrophysical Journal

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

19

ON THE IMPACT OF THREE DIMENSIONS IN SIMULATIONS OF NEUTRINO-DRIVEN CORE-COLLAPSE SUPERNOVA EXPLOSIONS

Journal:

The Astrophysical Journal

Year:

2013

Language:

english

File:

PDF, 610 KB

english, 2013

20

CHARACTERIZING THE CONVECTIVE VELOCITY FIELDS IN MASSIVE STARS

Chatzopoulos, Emmanouil, Graziani, Carlo, Couch, Sean M.

Journal:

The Astrophysical Journal

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

21

ERRATUM: “CHARACTERIZING THE CONVECTIVE VELOCITY FIELDS IN MASSIVE STARS” (2014, ApJ, 795, 92)

Chatzopoulos, E., Graziani, C., Couch, Sean M.

Journal:

The Astrophysical Journal

Year:

2015

Language:

english

File:

PDF, 238 KB

english, 2015

22

Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

Easton, Douglas F., Pharoah, Paul D.P., Antoniou, Antonis C., Tischkowitz, Marc, Tavtigian, Sean V., Nathanson, Katherine L., Devilee, Peter, Meindl, Alfons, Couch, Fergus J., Southey, Melissa, Goldga

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 207 KB

english, 2015

23

ASPHERICAL CORE-COLLAPSE SUPERNOVAE IN RED SUPERGIANTS POWERED BY NONRELATIVISTIC JETS

Couch, Sean M., Wheeler, J. Craig, Milosavljević, Miloš

Journal:

The Astrophysical Journal

Year:

2009

Language:

english

File:

PDF, 2.68 MB

english, 2009

24

Implicit large eddy simulations of anisotropic weakly compressible turbulence with application to core-collapse supernovae

Radice, David, Couch, Sean M, Ott, Christian D

Journal:

Computational Astrophysics and Cosmology

Year:

2015

Language:

english

File:

PDF, 2.40 MB

english, 2015

25

THE THREE-DIMENSIONAL EVOLUTION TO CORE COLLAPSE OF A MASSIVE STAR

Couch, Sean M., Chatzopoulos, Emmanouil, Arnett, W. David, Timmes, F. X.

Journal:

The Astrophysical Journal

Year:

2015

Language:

english

File:

PDF, 882 KB

english, 2015

26

A 66 year-old woman with hemoptysis

Patel, Falin B., Couch, Kara S., McNish, Sean, Miller, Jonathan D., Siegel, Robert, Easley, Samantha, Shanmugam, Victoria K.

Journal:

Arthritis Care & Research

Year:

2015

Language:

english

File:

PDF, 1.99 MB

english, 2015

27

Continuity of Medication Supply and Provision of Patient Information on Discharge: Development of a Survey Tool

Couch, Gabrielle, Quah, Sean Minn, Ng, Yee Ching, McKellar, Alice

Journal:

Journal of Pharmacy Practice and Research

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

28

Functional imaging of the lungs with gas agents

Kruger, Stanley J., Nagle, Scott K., Couch, Marcus J., Ohno, Yoshiharu, Albert, Mitchell, Fain, Sean B.

Journal:

Journal of Magnetic Resonance Imaging

Year:

2016

Language:

english

File:

PDF, 914 KB

english, 2016

29

The Shape of Cas A

Wheeler, J. Craig, Maund, Justyn R., Couch, Sean M.

Journal:

The Astrophysical Journal

Year:

2008

Language:

english

File:

PDF, 320 KB

english, 2008

30

Postoperative wound dehiscence: Predictors and associations

Shanmugam, Victoria K., Fernandez, Stephen J., Evans, Karen Kim, McNish, Sean, Banerjee, Anirban N., Couch, Kara S., Mete, Mihriye, Shara, Nawar

Journal:

Wound Repair and Regeneration

Year:

2015

Language:

english

File:

PDF, 91 KB

english, 2015

31

Shock Vorticity Generation from Accelerated Ion Streaming in the Precursor of Ultrarelativistic Gamma‐Ray Burst External Shocks

Couch, Sean M., Milosavljević, Miloš, Nakar, Ehud

Journal:

The Astrophysical Journal

Year:

2008

Language:

english

File:

PDF, 154 KB

english, 2008

32

NEUTRINO-DRIVEN CONVECTION IN CORE-COLLAPSE SUPERNOVAE: HIGH-RESOLUTION SIMULATIONS

Radice, David, Ott, Christian D., Abdikamalov, Ernazar, Couch, Sean M., Haas, Roland, Schnetter, Erik

Journal:

The Astrophysical Journal

Year:

2016

Language:

english

File:

PDF, 1.75 MB

english, 2016

33

LIGHT CURVES OF CORE-COLLAPSE SUPERNOVAE WITH SUBSTANTIAL MASS LOSS USING THE NEW OPEN-SOURCE SUPERNOVA EXPLOSION CODE (SNEC)

Morozova, Viktoriya, Piro, Anthony L., Renzo, Mathieu, Ott, Christian D., Clausen, Drew, Couch, Sean M., Ellis, Justin, Roberts, Luke F.

Journal:

The Astrophysical Journal

Year:

2015

Language:

english

File:

PDF, 2.35 MB

english, 2015

34

ASPHERICAL SUPERNOVA SHOCK BREAKOUT AND THE OBSERVATIONS OF SUPERNOVA 2008D

Couch, Sean M., Pooley, David, Wheeler, J. Craig, Milosavljević, Miloš

Journal:

The Astrophysical Journal

Year:

2011

Language:

english

File:

PDF, 5.86 MB

english, 2011

35

Relationship between Opioid Treatment and Rate of Healing in Chronic Wounds

Shanmugam, Victoria K., Couch, Kara S., McNish, Sean, Amdur, Richard L.

Journal:

Wound Repair and Regeneration

Year:

2016

Language:

english

File:

PDF, 957 KB

english, 2016

36

IDENTIFICATION OF FAINT CHANDRA X-RAY SOURCES IN THE CORE-COLLAPSED GLOBULAR CLUSTER NGC 6397: EVIDENCE FOR A BIMODAL CATACLYSMIC VARIABLE POPULATION

Cohn, Haldan N., Lugger, Phyllis M., Couch, Sean M., Anderson, Jay, Cool, Adrienne M., van den Berg, Maureen, Bogdanov, Slavko, Heinke, Craig O., Grindlay, Jonathan E.

Journal:

The Astrophysical Journal

Year:

2010

Language:

english

File:

PDF, 4.31 MB

english, 2010

37

THE DEPENDENCE OF THE NEUTRINO MECHANISM OF CORE-COLLAPSE SUPERNOVAE ON THE EQUATION OF STATE

Journal:

The Astrophysical Journal

Year:

2013

Language:

english

File:

PDF, 2.09 MB

english, 2013

38

COLLAPSAR ACCRETION AND THE GAMMA-RAY BURST X-RAY LIGHT CURVE

Lindner, Christopher C., Milosavljević, Miloš, Couch, Sean M., Kumar, Pawan

Journal:

The Astrophysical Journal

Year:

2010

Language:

english

File:

PDF, 6.33 MB

english, 2010

39

The mechanism(s) of core-collapse supernovae

Journal:

Philosophical Transactions Mathematical Physical & Engineering Sciences

Year:

2017

Language:

english

File:

PDF, 857 KB

english, 2017

40

Two-dimensional Core-collapse Supernova Explosions Aided by General Relativity with Multidimensional Neutrino Transport

O’Connor, Evan P., Couch, Sean M.

Journal:

The Astrophysical Journal

Year:

2018

Language:

english

File:

PDF, 2.56 MB

english, 2018

41

Core-Collapse Supernova Simulations including Neutrino Interactions from the Virial EOS

O’Connor, Evan, Horowitz, C. J., Lin, Zidu, Couch, Sean

Journal:

Proceedings of the International Astronomical Union

Year:

2017

Language:

english

File:

PDF, 456 KB

english, 2017

42

248 - Non-Targeted Metabolomics Profile can Differentiate Nonalcoholic Fatty Liver Disease (NAFLD) Patients with Coronary Artery Disease (CAD)

Elsheikh, Elzafir, Couch, Robin, Dailey, Allyson, Felix, Sean C., Jeffers, Thomas, Younoszai, Zahra, Allawi, Hussain, Gogoll, Trevor, Younossi, Mina, Paik, James, Lam, Brian P., Tran, Henry A., Schnei

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 532 KB

english, 2018

43

Co-occurrence of Anaerobes in Human Chronic Wounds

Choi, Yongwook, Banerjee, Anirban, McNish, Sean, Couch, Kara S., Torralba, Manolito G., Lucas, Sarah, Tovchigrechko, Andrey, Madupu, Ramana, Yooseph, Shibu, Nelson, Karen E., Shanmugam, Victoria K., C

Journal:

Microbial Ecology

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

44

Global comparison of core-collapse supernova simulations in spherical symmetry

O’Connor, Evan, Bollig, Robert, Burrows, Adam, Couch, Sean, Fischer, Tobias, Janka, Hans-Thomas, Kotake, Kei, Lentz, Eric J, Liebendörfer, Matthias, Messer, O E Bronson, Mezzacappa, Anthony, Takiwaki,

Journal:

Journal of Physics G Nuclear and Particle Physics

Year:

2018

Language:

english

File:

PDF, 1.72 MB

english, 2018

45

Exploring Fundamentally Three-dimensional Phenomena in High-fidelity Simulations of Core-collapse Supernovae

O’Connor, Evan P., Couch, Sean M.

Journal:

The Astrophysical Journal

Year:

2018

Language:

english

File:

PDF, 2.23 MB

english, 2018

46

Cancer susceptibility gene mutations in type I and II endometrial cancer

Long, Beverly, Lilyquist, Jenna, Weaver, Amy, Hu, Chunling, Gnanaolivu, Rohan, Lee, Kun Y., Hart, Steven N., Polley, Eric C., Bakkum-Gamez, Jamie N., Couch, Fergus J., Dowdy, Sean C.

Journal:

Gynecologic Oncology

Year:

2018

Language:

english

File:

PDF, 373 KB

english, 2018

47

Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology

Mandikian, Danielle, Figueroa, Isabel, Oldendorp, Amy, Rafidi, Hanine, Ulufatu, Sheila, Schweiger, Michelle G., Couch, Jessica A., Dybdal, Noel, Joseph, Sean B., Prabhu, Saileta, Ferl, Gregory Z., Bos

Journal:

The AAPS Journal

Year:

2018

Language:

english

File:

PDF, 968 KB

english, 2018

48

Turbulence in core-collapse supernovae

Radice, David, Abdikamalov, Ernazar, Ott, Christian D, Mösta, Philipp, Couch, Sean M, Roberts, Luke F

Journal:

Journal of Physics G Nuclear and Particle Physics

Year:

2018

Language:

english

File:

PDF, 2.17 MB

english, 2018

49

The impact of different neutrino transport methods on multidimensional core-collapse supernova simulations

Pan, Kuo-Chuan, Mattes, Carlos, O’Connor, Evan P, Couch, Sean M, Perego, Albino, Arcones, Almudena

Journal:

Journal of Physics G Nuclear and Particle Physics

Year:

2019

Language:

english

File:

PDF, 1.94 MB

english, 2019

50

Equation of State Dependent Dynamics and Multi-messenger Signals from Stellar-mass Black Hole Formation

Pan, Kuo-Chuan, Liebendörfer, Matthias, Couch, Sean M., Thielemann, Friedrich-Karl

Journal:

The Astrophysical Journal

Year:

2018

Language:

english

File:

PDF, 2.45 MB

english, 2018